1-[4-(dihydroxyboryl)phenyl]cyclopropanecarboxylic acid

1-[4-(dihydroxyboryl)phenyl]cyclopropanecarboxylic acid - Names and Identifiers

Name	1-(4-Boronophenyl)cyclopropanecarboxylic acid
Synonyms	EOS-60829 4-(1-Carboxycyclopropyl)phenylboronic acid 1-(4-Boronophenyl)cyclopropanecarboxylic acid 4-(1'-CARBOXYL-CYCLOPROPYL)PHENYLBORONIC ACID 1-(4-boronophenyl)cyclopropane-1-carboxylicacid Cyclopropanecarboxylic acid, 1-(4-boronophenyl)- 1-[4-(dihydroxyboryl)phenyl]cyclopropanecarboxylic acid
CAS	1159489-46-9

1-[4-(dihydroxyboryl)phenyl]cyclopropanecarboxylic acid - Physico-chemical Properties

Molecular Formula	C10H11BO4
Molar Mass	206
Density	1.38±0.1 g/cm3(Predicted)
Boling Point	445.1±55.0 °C(Predicted)
pKa	4.23±0.20(Predicted)
Storage Condition	under inert gas (nitrogen or Argon) at 2-8°C
Sensitive	Irritant
MDL	MFCD09037835

1-[4-(dihydroxyboryl)phenyl]cyclopropanecarboxylic acid - Introduction

1-(4-Boronophenyl)cyclopropanecarboxylic acid is an organic compound containing a boron group. The following is a description of its nature, use, formulation and safety information:

Nature:
-Appearance: White crystal or crystalline powder
-Molecular formula: C10H9BO2
-Molecular weight: 164.99g/mol
-Melting point: about 130-133°C
-Solubility: Soluble in some organic solvents, such as dimethyl sulfoxide and dimethyl formamide

Use:
- 1-(4-Boronophenyl)cyclopropanecarboxylic acid is mainly used for C- C bond formation reactions in organic synthesis. It can be used as a catalyst precursor for catalytic asymmetric hydrogenation reactions and asymmetric carbon-carbon bond formation reactions.
-This compound is also commonly used in the fields of pharmaceutical synthesis, materials science and organic optoelectronic devices.

Preparation Method:
The preparation of -1-(4-Boronophenyl)cyclopropanecarboxylic acid usually involves a multi-step reaction. One common method is to first synthesize phenylcyclopropanoyl chloride and then react with a borophenyl Grignard reagent to obtain the desired product.

Safety Information:
-The toxicity and safety data of this compound are limited, so appropriate protective measures should be taken when handling.
-In case of contact with skin, eyes or inhalation of the compound, rinse immediately with plenty of water and seek medical assistance.
-Avoid inhaling dust and skin contact during operation.
-Operate in a well-ventilated area and wear appropriate personal protective equipment, such as gloves, goggles and protective clothing.
-During use and storage, safe operating procedures and correct laboratory practices should be observed.

Last Update：2024-04-09 20:49:11